I can not comment on it's reliability for road work as I have only been using it at home. But if you're careful I do not know why it shouldn't hold up. Hey, if I remember right didn't Loungelizard mention that he had been placing the control unit on his sub? I would not doubt that over a bit of time all that vibrations is going to cause some kind of problems to the control unit.
That sub woofer kicks out a LOT of bottem end! I would not expect any mixer. amp, effect unit or any other piece of electronic equipment to hold up very long if it is sitting on top of a blasting sub-woofer.
If indeed that was the case of Loungelizard.
I know heard somebody mention that's what they were doing.
I like my 5500's a lot. And once again want to thank Gary and others for their input.

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The old Newb