With vArranger you can
Load a midifile, tune it
Use Soundfonts SF2 samples with the virtual synth
Use VST reverbs, fx...
Press REC and get a WAV or MP3 of the final recoring
No need to plug anything. Just a PC computer
Sounds can be very good because of RAM limit that can be huge
All stay in digital domain, and there is no ADC converter involved

It is so easy to do...