Wow, Russ, it's not music, it's no time for you.
Here's what I see that may help and it may not. Cuz maybe they're selfish jerks.
I'd go to the four kids of your friend and in no uncertain terms, I'd tell them they need to take over carting him around. I would not be mean but I would not be nicey nicey and apologetic. I'd be matter-of-fact and truthful. And I wouldn't ask, I'd tell them. I'm sure you could do it diplomatically but effectively.
Then, if that doesn't work, at least you tried. This is all assuming that they are aware of what all you do. If they don't, I'd be a bit easier. Then again, Dr. Phil might say I don't know what I'm talking about.
But my gosh, it's not like you don't have enough going on in your own family.
Whatever, that sucks. You are going to end up with a heart attack or stroke. Life is short.
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Bill