The secret to eliminating wrist pain is no secret at all. There have been several posts about this problem in the past, and the solution is quite simple.
First and foremost, your forearms should be parallel to the floor and your upper arms nearly vertical. The wrists should be nearly flat with the floor as well and the fingers should be curved as if you were holding a tennis ball. The same technique is used by secretarial staff that spend endless hours every day typing.
Naturally, in order to acheive this you will have to adjust your keyboard or sitting height appropriately.
The other thing that makes a big difference is not pounding on the keyboard's keys like a piano player. Not only is this hard on the joints of the hand and wrist, it's hard on the keyboard's rubber keypads. I couldn't count the number of people I've encountered that type lightly on a computer's keyboard, but pound the hell out of a synth's keys as if they're trying to imitate Jerry Lee Lewis. Lighten up and the pain mysteriously vanishes.
Good Luck,
Gary
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Travlin' Easy