Hello James,
Yes vArranger is a portable app.
You just need to install a small plugin for the audio features on the computer you will use
You don't need to run vArranger from your USB key. It's better (run faster) to copy the files in your computer hard drive.
Just plug the key on the computer.
Ask to your wife to not loose you usb key, as if it was a diamond

By the way, I am here to help my users not to bother too much about activations, but play music.
All the data are loaded into RAM.
For now, I don't like the idea of streaming from hd while giging

For now, Max 4GB of samples
Feel free to ask any questions
Dan