I only use the transpose on a few SMF. I can play in any key although not by sight. I do think memorization would be easier if you played everything in C. The patterns and cadences would be more easily recognizable.
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Bill in SC --- Roland BK9 (2) Roland BK7M, Roland PK5 Pedals, Roland FP90, Roland CM30 (2), JBL Eon Ones (2) JBL 610 Monitor, Behringer Sub, EV mics, Apple iPad (2) Behringer DJ mixer