The TB-303's knob controls can't be transmitted via MIDI or can it receive any MIDI system exclusive data like that from CUBASE or any other MIDI software or hardware . The TB-303 was made before MIDI was introduced and quickly discontinued . It was a failure is sales and did not gain any popularity until the thing was used in making house records . I remember back in 1982 the music stores coundn't give them away . By 1987 they were being sold for $25.00 brand new in a box here in Atlanta Georgia . I bought 6 of them . It was wierd , I also bought an SH-101 and MC-202 for $100.00 brand new as well . Rhythm City had them stacked up to the ceiling . They thought I was crazy . But , to answer you're question , no , the TB-303 does not respond to MIDI at all except for it's internal clock . A SYNC to MIDI converter is used for that .