If we're talking inversion (rotating upward/downward by a 180 degrees) then no. The difference is not audible.
However, if you mix the two (original and inverted together) they will cancel each other out.
I'm too tired to go on. Morph should take over.
Good night,
EDIT:
Well, I'm back.
Indeed, as mentioned below if you use one as a modulation source the difference can be quite dramatic. unFortunately only a few synths allow for this.
-ED-
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A gentleman is one who never hurts anyone's feelings unintentionally.
- - - Oscar Wilde [This message has been edited by 3351 (edited 02-14-2006).]